Selected Publications
Statistical Methods and Applications for Omics Data
RUV-III-NB: Normalization of single cell RNA-seq Data. Nucleic Acids Research. Accepted. DOI: https://doi.org/10.1093/nar/gkac486
Assessing and removing the effect of unwanted technical variations in microbiome data. biorxiv. preprint.
DECENT: differential expression with capture efficiency adjustmeNT for single-cell RNA-seq data. Bioinformatics.
Single-cell profiling of breast cancer T cells reveals a tissue-resident memory subset associated with improved prognosis. Nature Medicine.
Accessory subunits are integral for assembly and function of human mitochondrial complex I. Nature.
Risk Prediction Models
Concordant peripheral lipidome signatures in two large clinical studies of Alzheimer’s disease. Nature Comunications.
Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke. Nature Communications.
Comparisons of risk prediction methods using nested case‐control data. Statistics in Medicine.
Breast cancer risk assessment using genetic variants and risk factors in a Singapore Chinese population. Breast Cancer Research.
